Effects of Aprotinin on Pulmonary Vascular Resistance
نویسندگان
چکیده
منابع مشابه
Aprotinin Attenuates the Elevation of Pulmonary Vascular Resistance After Cardiopulmonary Bypass
Pulmonary vascular resistance (PVR) is generally believed to be elevated after cardiopulmonary bypass (CPB) due to whole body inflammation. Aprotinin has an antiinflammatory action, and it was hypothesized that aprotinin would attenuate the PVR increase induced by CPB. Ten mongrel dogs were placed under moderately hypothermic CPB for 2 hr. The experimental animals were divided into a control gr...
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IN THE FOREGOING communication Hiirlimann and Wiggers reported that the blood flow of a lung lobe perfused under constant pressure was reduced during progressively developing anoxia. It could not be determined from these experiments whether the increased pulmonary vascular resistance resulted from direct action of anoxia or involved indirect reactions; nor could the site of action be assessed. ...
متن کاملEffect of Oxygen on Pulmonary Vascular Resistance
L OWERED concentrations of oxygen in the inspired air have been shown to produce constriction of pulmonary vessels in the cat' 2 and in human subjects.3 4 The reaction of canine pulmonary vessels to hypoxia has been studied by many workers, whose consensus appears to favor a constrictor response. However, its variability has caused LanariZubiaur and Hamilton5 to question its biologic significan...
متن کاملPulmonary vascular resistance.
where P represents the pressure gradient between the pulmonary artery and the pulmonary vein, F, the blood flow per unit time, and R. the vascular resistance. For a given pressure gradient and flow rate, R will be determined, among other things, by the physical dimensions of the chaniiels that the blood traverses. In a rigid hydraulic system this formula applies over a wide range of flow and pr...
متن کاملPulmonary Vascular Resistance
where P represents the pressure gradient between the pulmonary artery and the pulmonary vein, F, the blood flow per unit time, and R. the vascular resistance. For a given pressure gradient and flow rate, R will be determined, among other things, by the physical dimensions of the chaniiels that the blood traverses. In a rigid hydraulic system this formula applies over a wide range of flow and pr...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1999
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-199904020-00241